Visceral leishmaniasis (VL) is caused by the dissemination of the
protozoan parasite Leishmania donovani throughout the reticuloendothelial
system. This systemic disease may mimic or lead to
several types of hematological disorders including hemophagocytic
lymphohistiocytosis (HLH). Infection associated hemophagocytic
syndrome caused by Leishmania is very rare and difficult
to diagnose. Herein, we describe an infant with HLH associated
with VL. The severity of HLH secondary to visceral leishmaniasis
ranges from pure biological forms that resolve with antimicrobial
therapy to life-threatening emergencies that require specific
treatment. Our patient was treated with meglumine antimoniate.
The outcome of the disease was favorable with a follow-up of
12 months.
Key words: Leishmaniasis ▪ Hemophagocytic lymphohistiocytosis


Current View
Click here to download the PDF file.

Add new comment

Plain text

  • No HTML tags allowed.
  • Web page addresses and e-mail addresses turn into links automatically.
  • Lines and paragraphs break automatically.
This question is for testing whether or not you are a human visitor and to prevent automated spam submissions.
Enter the characters shown in the image.

About Us

A Platform for experts to develop and test evidence based strategies for the treatment and control of Leishmaniasis.


Social media

Contact Us

SECID - Rruga Aleksander Moisiu, Nr. 80, Tirana, Albania 

Tel. +355 68 20 69 698 
Fax. +355 4370058